Artificial gene synthesis is a critically important technique in modern synthetic biology. The ability to easily customize and create DNA sequences based off of a single gene, gene clusters, or completely from scratch enables an enormous amount of versatility and a wide range of applications for synthetic DNA. The necessity of long gene synthesis Researchers […]
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The Application of Synthetic Biology to Human Health and Medicine
Synthetic biology is a new interdisciplinary subject established in bioinformatics, DNA synthetic technology, genetics, and systems biology. Synthetic biology is the rational and systematic design/construction of biological systems with desired functionality. One of its most powerful tools is DNA synthesis technology; recently, the cost of gene synthesis has dropped 10 fold over the past 15 […]
Synthetic Biology and Drug Discovery
Synthetic biology utilizes information from fields such as biotechnology, molecular biology, molecular engineering, and many more in order to design and build novel biological functions and systems. Synthetic biology is the engineering of biology itself, and will have profound implications on all levels of biological structure. One of the applications of synthetic biology is to […]
How Synthetic Biology Leads to Renewable Energy
Synthetic Biology aims to engineer the nature organisms that the system can perform new fuction or construct new material. Biofuel refers to solid, liquid, or gaseous fuel produced through contemporary biological processes, such as agriculture and anaerobic digestion. Biofuel has great potential to replace petroleum, gasoline, and diesel, and is an important factor in the […]
GC-Rich Gene Synthesis
Gene synthesis is the technology of artificially synthesizing double-stranded DNA in vitro, and is a crucially important technique in molecular biology. Conventional gene synthesis generally involves assembling small segments of DNA and/or amplifying known samples of genetic material, and requires the raw nucleobases guanine, cytosine, adenine, thymine and uracil as starting materials. GC-content (guanine-cytosine content) […]
Brief Introduction and Advantages of Antibody Library Techniques
Antibody library techniques have not only enabled the simple and convenient production of genetically engineered antibodies, but have also provided a new way to manufacture humanized antibodies. The antibody library was first amplified from B cells by PCR in the heavy and light chain of the antibody and then ligated into the appropriate vector to […]
Antibody Library Technology Screen Out the Specific Antibody
Humanized antibodies are derived from non-human species, modified to more closely resemble existing, natural human antibodies. Their applications have a great deal of potential in medicine and immunology due to the wide range of variability that humanized antibodies provide. Compared with heterologous antibodies, they also circumvent certain immune side effects to the human body. From […]
Gene Synthesis in Genetic Engineering
Gene synthesis has revolutionized what was once thought to be impossible in the field of genetics. Synthesis of the first gene, a yeast tRNA, was achieved by Har Gobind Khorona and coworkers in 1972. Since then this technology has had long last impacts on genetic research and the biotechnology industry. Whether it is synthesizing small […]
Effects of the Syno® Platform in Gene Synthesis Industry
Recently, gene synthesis has become an extremely popular and effective method to conduct genetic research. This rise in popularity stems from the ease of use as well as the effective results. In short, gene synthesis can be described as the creation of a synthetic genetic sequence specified by the user. Recently, the genetic sequence of […]
Gene Synthesis Expression Vector
Gene synthesis is a fundamental technique in synthetic biology, allowing for the creation of unique synthetic genes that would be difficult or impossible to obtain naturally. In order to express a synthetic gene in an efficient and controlled way, expression vectors are often used to introduce the gene into a cell, after which the cell’s […]
Gene Synthesis and Cloning
Gene Synthesis and Cloning is an integral part of many research pipelines. There are two popular methods of genetic cloning: DNA amplification by use of subcloning and polymerase chain reaction (PCR). The former needs more time and resource consuming, while the latter spends less time and cost effectively. Traditionally, subcloning was commonly used for amplification. […]
Antibody Library Applications
The application of antibodies has expanded from being an immunologically important protein to an important research tool and a rapidly growing class of therapeutic agents. Since the successful generation of monocolonal antibodies from antibody libraries in 1980’s, many biotech companies and research institutes started constructing antibody libraries. Depending on the methods of construction, antibody libraries […]
Gene Synthesis Methods and Applications
Introduction Over the last few decades, gene synthesis and assembly technology have developed rapidly. Since the 1960s, our capability to synthesize genes has skyrocketed from less than 100bp to more than 1,000,000bp. Gene synthesis methods and applications have a profound impact in metabolic engineering, genetic network design, and vaccine design. However, existing gene synthesis methods […]
Gene Synthesis Codon Optimization
Gene synthesis refers to the technology of artificially synthesizing double-stranded DNA molecules in vitro through reverse transcription of mRNA of a known template gene. Intelligent synthetic gene design is critical to gene engineering and the efficient production of recombinant protein through heterologous hosts. Unfortunately, not all genes can be successfully and effectively expressed in heterologous […]
Gene Synthesis Applications：gene cloning technology and application
Gene synthesis was first successfully conducted in 1972 on a yeast tRNA by Har Gobind Khrona and associates.Since 1972, the technology and mechanisms of gene synthesis have flourished in order to successfully obtain the genetic sequence specific to a wide range of research topics.Gene synthesis offers many major advantages over the traditional gene cloning methods: […]
Gene Library Synthesis : genomic libraries and cDNA libraries
Gene synthesis has revolutionized genetic research over the past twenty years by allowing the convenience of DNA storage for a wide range of genome sizes. These libraries have allowed researchers to archive the genes of interested and be able to obtain each gene with relative ease at his or her leisure. Another great advantage ofgene […]
Applications of PCR Cloning Technology
PCR cloning technology can amplify trace amounts of DNA, generating millions of copies of a specific DNA sequence. PCR is highly sensitive, extremely specific, and high-yield, while also being easily reproducible, fast, and convenient, making it an amazingly powerful tool in molecular biology. With the rapid development of modern life science, PCR cloning technology has […]
Gene Synthesis Driving Synthetic Biology Applications
DNA sequencing has been vital to the development of synthetic biology in many ways. Sequencing enables researchers to determine the DNA sequence in just about any gene, and enables the construction of vast databases that can hold entire genomes. Genome databases are an important resource for downstream synthetic biology applications such as protein expression, directed […]
Synbio Technologies’ Gene Synthesis Process
Synbio Technologies’s proprietary Syno®2.0 gene synthesis process includes computational design of short oligos, which can then be reliably synthesized, assembled, and cloned into the desired vector. An available precursor to this process is optimization of the gene sequence for improved protein expression and other purposes. Fig. 1 Syno®2.0 gene synthesis processA large number of oligos […]
The Methods of PCR Cloning
PCR Cloning is a technique used to amplify a specific region of DNA strand, and is used in almost every molecular biology lab in the world. PCR can be used on almost any DNA region, provided that suitable primers can be made. Synbio Tech provides one-stop PCR cloning services, including primer design. PCR Primer Design […]
