At Synbio Technologies we pride ourselves in being one of the premier companies within not only the gene synthesis industry, but the biotechnology industry as a whole. This confidence is relying upon our tested and proven methods of gene synthesis. Gene synthesis can be defined as the method in synthetic biology used to engineer an […]
Tag: gene synthesis
Gene Synthesis Definition
The traditional method of studying a gene’s function is to extract the gene of interest, amplify it and put the resulting sequence through various molecular assessments. These assessments can vary from generating a frameshift mutation within the sequence, to upregulating the expression of the sequence in order to observe the resulting phenotypes the mutated sequence […]
Large Gene Synthesis
An interesting and important aspect of genetic research that has grown drastically in popularity over the last ten to fifteen years is gene synthesis . Gene synthesis can be defined as the construction of a physical genetic sequence from a requested sequence in text format. Gene synthesis allows us, at Synbio Technologies, to manufacture genetic […]
Gene Synthesis Vectors
A relatively recent discovery, dating back to the early 1970s, in biology has revolutionized the field of genetics research. This discovery is known as gene synthesis , which allows for the manufacturing of a physical genetic sequence from a string of base pairs in text format. Gene synthesis allows for the creation of a genetic […]
Gene Synthesis Promotion
After its discovery and first successful application of gene synthesis in the early 1970s, by Har Gobind Khorana and associates, it has become a frequently used method within genetics and other biological research fields. Gene synthesis has a simple definition but long lasting impacts on the genetics research community and various other fields of research. […]
Gene Synthesis Mutagenesis
One of the fundamental ways to study the function of a gene is to void, knockout, its function and observe the resulting phenotype. This void of function, commonly known as mutagenesis, has been practice within the field of genetics for many years and has been proven effective countless times. A more commonly utilized method of […]
Gene Synthesis Cost
Moore’s Law has been applied and shown in various industries ranging from the tech industry to the biotech industry. Moore’s Law has most notably shown within the field of genetics when analyzing the cost of sequencing the human genome. The first whole genome sequencing was conducted on a human in the early 2000s, and costed […]
Gene Synthesis by PCR
Prior to the 1970s traditional cloning was used in order to amplify a gene of interest. This process of gene synthesis by PCR is still used today, but relies on a laborious process of achieving the final amplified product. Traditional cloning relies on recombinant DNA being integrated into a bacteria host’s genome. Once the DNA […]
Molecular Biology Cloning
Molecular biology cloning Molecular cloning is one method in molecular biology that is commonly used to amplify a genetic sequence of interest. This is accomplished by inserting recombinant DNA into a vector which can then carry DNA fragments in host organisms to be amplified. This process of amplification is based on molecular biology standard, first […]
Introduction to Molecular Biology
Introduction to molecular biology Molecular biology is a subfield in biology that studies the various topics and molecular mechanisms within cells that are important for proper cellular function. These topics can include any cellular mechanism ranging from cellular metabolism to utilizing a molecular function in order to successfully accomplish gene synthesis. These topics and mechanisms […]
Long Gene Synthesis
Artificial gene synthesis is a critically important technique in modern synthetic biology. The ability to easily customize and create DNA sequences based off of a single gene, gene clusters, or completely from scratch enables an enormous amount of versatility and a wide range of applications for synthetic DNA. The necessity of long gene synthesis Researchers […]
GC-Rich Gene Synthesis
Gene synthesis is the technology of artificially synthesizing double-stranded DNA in vitro, and is a crucially important technique in molecular biology. Conventional gene synthesis generally involves assembling small segments of DNA and/or amplifying known samples of genetic material, and requires the raw nucleobases guanine, cytosine, adenine, thymine and uracil as starting materials. GC-content (guanine-cytosine content) […]
Gene Synthesis in Genetic Engineering
Gene synthesis has revolutionized what was once thought to be impossible in the field of genetics. Synthesis of the first gene, a yeast tRNA, was achieved by Har Gobind Khorona and coworkers in 1972. Since then this technology has had long last impacts on genetic research and the biotechnology industry. Whether it is synthesizing small […]
Effects of the Syno® Platform in Gene Synthesis Industry
Recently, gene synthesis has become an extremely popular and effective method to conduct genetic research. This rise in popularity stems from the ease of use as well as the effective results. In short, gene synthesis can be described as the creation of a synthetic genetic sequence specified by the user. Recently, the genetic sequence of […]
Gene Synthesis Expression Vector
Gene synthesis is a fundamental technique in synthetic biology, allowing for the creation of unique synthetic genes that would be difficult or impossible to obtain naturally. In order to express a synthetic gene in an efficient and controlled way, expression vectors are often used to introduce the gene into a cell, after which the cell’s […]
Gene Synthesis and Cloning
Gene Synthesis and Cloning is an integral part of many research pipelines. There are two popular methods of genetic cloning: DNA amplification by use of subcloning and polymerase chain reaction (PCR). The former needs more time and resource consuming, while the latter spends less time and cost effectively. Traditionally, subcloning was commonly used for amplification. […]
Gene Synthesis Methods and Applications
Introduction Over the last few decades, gene synthesis and assembly technology have developed rapidly. Since the 1960s, our capability to synthesize genes has skyrocketed from less than 100bp to more than 1,000,000bp. Gene synthesis methods and applications have a profound impact in metabolic engineering, genetic network design, and vaccine design. However, existing gene synthesis methods […]
Gene Synthesis Codon Optimization
Gene synthesis refers to the technology of artificially synthesizing double-stranded DNA molecules in vitro through reverse transcription of mRNA of a known template gene. Intelligent synthetic gene design is critical to gene engineering and the efficient production of recombinant protein through heterologous hosts. Unfortunately, not all genes can be successfully and effectively expressed in heterologous […]
Gene Synthesis Applications：gene cloning technology and application
Gene synthesis was first successfully conducted in 1972 on a yeast tRNA by Har Gobind Khrona and associates.Since 1972, the technology and mechanisms of gene synthesis have flourished in order to successfully obtain the genetic sequence specific to a wide range of research topics.Gene synthesis offers many major advantages over the traditional gene cloning methods: […]
Gene Library Synthesis : genomic libraries and cDNA libraries
Gene synthesis has revolutionized genetic research over the past twenty years by allowing the convenience of DNA storage for a wide range of genome sizes. These libraries have allowed researchers to archive the genes of interested and be able to obtain each gene with relative ease at his or her leisure. Another great advantage ofgene […]
