At Synbio Technologies we pride ourselves in being one of the premier companies within not only the gene synthesis industry, but the biotechnology industry as a whole. This confidence is relying upon our tested and proven methods of gene synthesis. Gene synthesis can be defined as the method in synthetic biology used to engineer an […]
Tag: Molecular Biology
Molecular Biology Evolution
Since molecular biology was first established, in the 1930s, the complexity of various biological systems have been explored in order to better understand these systems. As years went by, and our understanding of these systems increased, the information that fell under the, large and ever-growing, umbrella of “molecular biology” became more specific and eventually subdivided […]
Molecular Biology Cloning
Molecular biology cloning Molecular cloning is one method in molecular biology that is commonly used to amplify a genetic sequence of interest. This is accomplished by inserting recombinant DNA into a vector which can then carry DNA fragments in host organisms to be amplified. This process of amplification is based on molecular biology standard, first […]
Introduction to Molecular Biology
Introduction to molecular biology Molecular biology is a subfield in biology that studies the various topics and molecular mechanisms within cells that are important for proper cellular function. These topics can include any cellular mechanism ranging from cellular metabolism to utilizing a molecular function in order to successfully accomplish gene synthesis. These topics and mechanisms […]
Applications of Molecular Biology Techniques in Environmental Microbiology Research
Advances in molecular biology and genetic engineering technology, microbial genetic manipulations have promoted the application of microorganisms in in ecological and environmental research. Genetically engineered microorganisms are being developed and assessed for their beneficial uses in environmental monitoring, toxic chemicals pollution control and genetically engineered microorganisms. Hybridization probe The oligonucleotide probes can hybridize to DNA […]
Applications of PCR Cloning Technology
PCR cloning technology can amplify trace amounts of DNA, generating millions of copies of a specific DNA sequence. PCR is highly sensitive, extremely specific, and high-yield, while also being easily reproducible, fast, and convenient, making it an amazingly powerful tool in molecular biology. With the rapid development of modern life science, PCR cloning technology has […]
The Methods of PCR Cloning
PCR Cloning is a technique used to amplify a specific region of DNA strand, and is used in almost every molecular biology lab in the world. PCR can be used on almost any DNA region, provided that suitable primers can be made. Synbio Tech provides one-stop PCR cloning services, including primer design. PCR Primer Design […]
PCR Techniques in Biology
Polymerase chain reaction, generally known as PCR and also referred to as in vitro DNA amplification, is one of the most widely used techniques in biology labs across the world. Traditional DNA amplification method Traditional DNA amplification involves the construction of a vector containing the target gene, followed by the transfer of the vectors into […]
Codon Usage Bias
The genetic information in DNA is transcribed into mRNA then translated into protein, in which codons played important roles during the process. Total 64 combinations of nucleotide triplet (codon) encode all 22 amino acids. Each amino acid corresponds to at least one codon, e.g. methionine and tryptophan. In other cases, amino acids are encoded by […]
Synbio Technologies’ Codon Optimization Strategy
Translation is the last step in protein synthesis that results in stable proteins from DNA replication, mRNA transcription and modification in cells. Codon optimization aims to increase the yield of protein expression in different organisms by rebalancing usage of synonymous codons. High quality protein has a wide range of applications, including study of protein structure […]
Synbio Technologies’ NGTMCodon Optimization Software
Synbio Technologies’ proprietary NGTMCodon optimization software provides customers with free codon optimization services bundled with gene synthesis. Our NGTM Codon optimization software optimizes gene sequences based on different expression systems to maximize protein expression. NGTMCodon optimization software advantages： Elimination of codon usage bias: Codon usage bias refers to the differences in frequency of synonymous codons […]
Four Steps of Subcloning Technology Protocol
Subcloning refers to the technique of re-cloning a DNA fragment from one vector to another, so that we can more easily perform analysis, transformation, and recombination of the target gene(s). Subcloning is an important tool in any molecular biologist’s toolkit, helping to elucidate the function of a target gene and to easily analyze its phenotype. […]
Synbio Technologies’ PCR cloning and Subcloning Technology
PCR cloning and subcloning technology, first developed in the 1970s, is now a staple in every molecular biology lab in the world. Cloning allows researchers to much more easily understand gene function at a deeper level, and greatly facilitates gene editing. PCR cloning and subcloning technology is not only revolutionary for the field of biology, […]
A Brief Introduction of Molecular Biology Techniques
Molecular biology studies the morphology, structural features, biological relevance and regulatory mechanism of biological macromolecules including nucleic acid, protein and others. Molecular biology truly uncovered the mysteries of the biological world from the molecular level; it signaled the transition from passive adaption from nature to actively restructuring and reengineering the nature. The main research contents […]
The Wide Applications of Molecular Biology
Molecular biology clarifies regularities of cell and receals the essence of life.Molecular biology technologies have been widely adapted for recombinant protein production, genetic modification of organisms, gene therapy, environmental protection, etc. Production of recombinant proteins Recombinant Insulin production For very long time, the insulin that was used to treat diabetic patients is solely purified from […]
Applications of Molecular Biology Techniques in Environmental Microbiology Research
Advances in molecular biology and genetic engineering technology, microbial genetic manipulations have promoted the application of microorganisms in in ecological and environmental research. Genetically engineered microorganisms are being developed and assessed for their beneficial uses in environmental monitoring, toxic chemicals pollution control and genetically engineered microorganisms. Hybridization Probe The oligonucleotide probes can hybridize to DNA […]
