Gene synthesis refers to the technology of artificially synthesizing double-stranded DNA molecules in vitro through reverse transcription of mRNA of a known template gene. Intelligent synthetic gene design is critical to gene engineering and the efficient production of recombinant protein through heterologous hosts. Unfortunately, not all genes can be successfully and effectively expressed in heterologous […]
Category: Gene Synthesis
Gene Synthesis Applications：gene cloning technology and application
Gene synthesis was first successfully conducted in 1972 on a yeast tRNA by Har Gobind Khrona and associates.Since 1972, the technology and mechanisms of gene synthesis have flourished in order to successfully obtain the genetic sequence specific to a wide range of research topics.Gene synthesis offers many major advantages over the traditional gene cloning methods: […]
Gene Library Synthesis : genomic libraries and cDNA libraries
Gene synthesis has revolutionized genetic research over the past twenty years by allowing the convenience of DNA storage for a wide range of genome sizes. These libraries have allowed researchers to archive the genes of interested and be able to obtain each gene with relative ease at his or her leisure. Another great advantage ofgene […]
Gene Synthesis Driving Synthetic Biology Applications
DNA sequencing has been vital to the development of synthetic biology in many ways. Sequencing enables researchers to determine the DNA sequence in just about any gene, and enables the construction of vast databases that can hold entire genomes. Genome databases are an important resource for downstream synthetic biology applications such as protein expression, directed […]
Synbio Technologies’ Gene Synthesis Process
Synbio Technologies’s proprietary Syno®2.0 gene synthesis process includes computational design of short oligos, which can then be reliably synthesized, assembled, and cloned into the desired vector. An available precursor to this process is optimization of the gene sequence for improved protein expression and other purposes. Fig. 1 Syno®2.0 gene synthesis processA large number of oligos […]
Artificial Gene Synthesis and Traditional Molecular Cloning
Synbio Technologies is a professional company dealing with gene synthesis and cloning. The company can provide artificial gene synthesis and traditional molecular services through our Syno®1.0, Syno®2.0 and Syno®3.0 gene synthesis platforms. Our Syno® platforms can conduct a variety of functions, including construction of a humanized antibody library, optimization of industrial enzymes, chromosomes/genome synthesis, development […]
